Expression and Clinical Signficance of Survivin and Proliferating Cell Nuclear Antigen in Human Esophageal Carcinoma
- VernacularTitle:食管癌Survivin和PCNA的表达及其临床意义
- Author:
Jibin ZOU
;
Guangen HUANG
;
Honglian CHEN
- Publication Type:Journal Article
- Keywords:
Esophageal carcinoma;
Survivin;
PCNA;
Prognosis;
Immunohistochemistry
- From:
Journal of Chinese Physician
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and clinical significance of survivin and proliferating cell nuclear antigen(PCNA) in human esophageal carcinoma. [WTHZ]Methods The expression of survivin and PCNA was detected by immunohistochemical SP method in 98 cases of esophageal carcinoma and paired normal mucosa adjancent to tumor. Results The positive rate of survivin expression in esophageal carcinoma and normal mucosa adjancent to tumor was 80.6% and 7.1%, respectively, which was obviously higher in the former than in the latter(P