Comparison of The Effects of Healon(R) and BioLon(R) on Rabbit Eyeballs after Intracameral and Intravitreal Injections.
- Author:
Seung Moo RYU
1
;
Won Ki LEE
;
Kee Yong CHOI
Author Information
1. Department of Ophthalmology, National Medical Center, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
BioLon(R);
Healon(R);
Intracameral;
Intravitreal
- MeSH:
Aqueous Humor;
Intravitreal Injections*;
Sodium
- From:Journal of the Korean Ophthalmological Society
1995;36(9):1447-1453
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We conducted a study to compare the effects of Healon(R) and BioLon(R), which are sodium hyaluronates made by different raw materials, on rabbit eyeballs after intracameral and intravitreal injections. In the intracameral-injection group, aqueous humor was replaced with 0.2 ml of Healon(R) or BioLon(R), and in the intravitreal-injection group. 0.4 ml of Healon(R) or BioLon(R) was injected after the removal of the same amount of vitreous. Slitlamp and indirect ophthalmoscopic examination, measurement of IOP, and measurement of corneal thickness were performed preoperatively and at 2hours, 24 hours, 3 days, and 7 days postoperatively. Histopathologic examinaion was done at 7 days postoperatively. No group had significant differences in all tests(p>0.05) and the findings were normalized within 7 days. These results indicated that there were no significant differences between the Healon(R) and BioLon(R) groups in the effects on rabbit eyeballs after intracameral and intravitreal injections.
