Study on animal intracorneal implantation model with xenogeneic swine corneal stroma
- VernacularTitle:角膜体外重构异种生物载体材料植入性实验研究
- Author:
Jing WU
;
Nian HAO
;
Shuyan LI
;
Jintang XU
;
Yanping WANG
- Publication Type:Journal Article
- Keywords:
Corneal stroma;
Biocompatible materials;
Swine;
Cats
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). (2) In the total 12 rabbits, all the cornea grafts survived without rejection reaction, corneal haze or corneal neovascularization. The fresh grafts got transparent after 2 months, and the dehydrated grafts got transparent after 6 months. Histological study demonstrated both fresh and dehydrated stroma grafts had fused with rabbits'corneal stroma very well without lymphocytes infiltrating. (3) As shown in histological observations, the reconstructed cat corneal endothelial tissue was similar to the nature tissue. Cultured cat endothelial cells connected tightly to each other and attached to the Descemet's membrane closely. CONCLUSION: Swine corneal stroma has low immunogenicity and satisfying biocompatibility,it is an ideal biological carrier for cornea reconstruction in vitro.
