Changes of cellular immunological function after surgical operation in patients with locally advanced lung cancer
- VernacularTitle:中晚期肺癌患者手术前后细胞免疫功能变化
- Author:
Feng HONG
;
Gang XIONG
;
Ruixiang ZHANG
;
Jianming PENG
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Operation;
Immunity;
T lymphocyte subsets
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the change of cellular immunological function in patients with locally advanced lung cancer before and after operations. METHODS: A lung cancer group of 20 cases with locally advanced lung cancer (group A), a benign disease group of 20 cases with lung benign disease (group B) and a normal group of 20 cases from healthy volunteers (group C) were set up. The levels of the peripheral blood T lymphocyte subsets (CD~+_3, CD~+_4, CD~+_8, CD~+_4/ CD~+_8 ratio) were detected in the group A before operation and on the 10th day and 17th day after operation by indirect immuno-fluorescence assay and contrasted with the group B and group C. RESULTS: The levels of T lymphocyte subsets in group A were abnormal before operation, CD~+_3, CD~+_4/ CD~+_8 ratio were significantly lower than those in group B and group C (P
