Effect of Roxithromycin on Cellular Immune Function of Mice
- VernacularTitle:罗红霉素对小鼠细胞免疫功能的影响
- Author:
Wenfu HE
;
Xiaokang LIU
- Publication Type:Journal Article
- Keywords:
Roxithromycin;
Cell immunity;
Lymphocyte conversion ratio
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
S OBJECTIVE:To study the effect of roxithromycin on cellular immune function and to study its anti-in-flammatory and immunoregulation effects beside its antibacterial effect.METHODS:The mice were randomized into negative control group,roxithromycin(high,medium,low dosage group)groups and dexamethasone group,the splenic lymphocyte conversion ratio of each group was determined by in vivo method and in vitro method respectively after14days of intragastric administration of drugs.RESULTS:Compared with the negative control group,roxithromycin(high,medium,low dosage)groups could significantly reduce splenic lymphocyte conversion ratio of mice(P
