Determination of Camphor in Compound Menthol Nose Drop by RP-HPLC
- VernacularTitle:反相高效液相色谱法测定复方薄荷脑滴鼻液中樟脑的含量
- Author:
Jing TIAN
;
Yalin XU
;
Di YANG
- Publication Type:Journal Article
- Keywords:
RP-HPLC;
Compound menthol nose drop;
Camphor;
Content determination
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To determine camphor in compound menthol nose drop by RP-HPLC.METHODS:Waters No-va-pak C 18 was taken as the chromatographic column,the mobile phase was composed of chloroform-methanol-water(14∶52∶30)with a flow speed at1.0ml/min and detection wavelength at289nm,the column temperature was35℃.RESULTS:The linear range for camphor was0.8～5.6?g/ml(r=0.9998)and the average recovery rate was99.4%(RSD=0.7%).CONCLUSION:The method is specific,convenient and accurate,which can be used for the quality control of the preparation.
