Relationship between mucosal patterns of Barrett esophagus under magnifcation endoscopy and pa-thology
- VernacularTitle:Barrett食管放大内镜下分型与组织病理学关系的研究
- Author:
Jingjing ZHAO
;
Dianchun FANG
;
Chengping XU
;
Rang ZHANG
;
Yulin FAN
;
Xianghong LI
;
Guiyong PENG
;
Zhenhua WANG
- Publication Type:Journal Article
- Keywords:
Barrett esophagus;
Magnification chromoendoscopy;
Histopathology
- From:
Chinese Journal of Digestive Endoscopy
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationships among clinical features, endoscopic characteristics and pathologic epithelial types of Barrett esophagus. Methods Magnification chromoendoscopy ( MCE) was performed in 2506 patients with gastroesophageal reflux disease ( GERD) and 106 patients with Barrett esophagus in our hospital during Feb,2003 -Feb,2004 were analyzed. The clinical features, endoscopic characteristics, pathologic epithelial types and their relationships were analyzed. Results The symptoms of gastro esophageal reflux disease ( GERD) were the main presentation of Barrett esophagus but 27 (25. 5% ) cases without such presentation. Four types of mueosal patterns, dot pattern, ridge or villous pattern and irregular/distorted pattern. were noted within the columnar mucosa using high magnification endos-copy: There were three epithelial types within the columnar lined esophagus: intestinal metaplasia (IM ) , cardiac and fundie types. Three epithelial types were noted in the methylene blue staining areas; ridged/vil-lous pattern and irregular/distorted pattern, all of them were in epithelial types of intestinal metaplasia. Conclusion Magnification chromoendoscopy helps to identify areas with IM, and having important significance in diagnosis and clinical follow up of Barrett esophagus.
