Evaluation on gastric mucosal features of intestinal metaplasia by high-resolution magnifying endos-copy
- VernacularTitle:放大内镜对胃黏膜肠上皮化生及萎缩的观察研究
- Author:
Canghai WANG
;
Yongzheng YU
;
Zhonglin YU
- Publication Type:Journal Article
- Keywords:
Magnifying endoscopy;
Gastric intestinal metaplasia;
Gastric pits
- From:
Chinese Journal of Digestive Endoscopy
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristic findings of intestinal metaplasia revealed by magnifying endoscopy, and clarified their relationship with histopathological features. Methods One hundred and nine patients underwent magnifying endoscopy between March 2003 and November 2003. Patients with gastric adenocarcinoma, esophogeal and/or gastric varices, history of gastric surgery were excluded. Endoscopic examination was performed with a high-resolution magnification endoscope after methylene blue (1 % ) spraying. According to the differences in color and mucosal pattern, forms of endoscopic images were defined, and biopsies were taken (n = 115). Results Six patterns of endoscopic images were defined according to the microscopic findings. Pattern-4 and -5 were related to intestinal metaplasia. Histological features were used as the key standard. Conclusion High-resolution magnifying endoscopy is useful in detecting intestinal metaplasia of gastric mucosa pits from its normal shape changed into oval shape or villous like pattern. This procedure may improve the follow-up of individuals at high-risk of gastric cancer.
