The Clinical Study of Postoperative Chemotherapy and Administration Pathways in Primary Hepatocellular Carcinoma Patients with Portal Vein Tumor Thrombus
- VernacularTitle:原发性肝癌合并门静脉癌栓术后化疗途径和给药方式的临床研究
- Author:
Yongzhong WANG
;
Xuwu WEI
;
Shukai XU
- Publication Type:Journal Article
- Keywords:
Carcinoma,Hepatocellular;
Portal vein;
Tumor thrombus;
Chemotherapy
- From:
Journal of Chinese Physician
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic effect of different postoperative chemotherapy and administration pathways in primary hepatocellular carcinoma (PHC) patients with portal vein tumor thrombus (PVTT). Methods 60 PHC patients with PVTT were divided into A, B, C and D groups. A group was treated by transcatheter arterial chemo-embolization (TACE); B group was treated by TACE and portal vein intubation(PVI) with quick intravenous injection; C group was treated by TACE and PVI with slow infusion controlled by computer; and D group was treated by hepatic arterial intubation chemo-embolization (HAI) and PVI with slow infusion controlled by computer. Results The survival rate among groups A, B and C had a significant difference (P0.05). Conclusion PHC patients with PVTT could be treated by both hepatic arterial chemotherapy and portal vein chemotherapy throug portal vein continuous infusion. TACE or HAI was suitable for postoperative chemotherapy.