Recent Update in Diabetic Nephropathy.
10.3904/kjm.2015.89.3.265
- Author:
Nan Hee KIM
1
Author Information
1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. nhkendo@gmail.com
- Publication Type:Review
- Keywords:
Diabetic nephropathies;
Albuminuria;
Renal insufficiency, Chronic;
Diagnosis;
Therapeutics
- MeSH:
Albuminuria;
Blood Glucose;
Blood Pressure;
Cardiovascular Diseases;
Diabetic Nephropathies*;
Diagnosis;
Kidney Diseases;
Kidney Failure, Chronic;
Prevalence;
Renal Insufficiency, Chronic;
Renin-Angiotensin System;
Standard of Care
- From:Korean Journal of Medicine
2015;89(3):265-270
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Diabetic nephropathy is the leading cause of end-stage renal disease, and is associated with increased risk of cardiovascular disease. Optimal control of blood glucose and blood pressure based on the blockade of renin-angiotensin system is the standard of care for the prevention and treatment of diabetic nephropathy. Regardless of these therapies, the prevalence of diabetic nephropathy continues to increase, highlighting the need for additional therapies. Diabetes affects the progression of kidney disease through a variety of mechanisms; several new therapeutic agents targeting these pathways have been developed, with currently being evaluated in clinical trials.
