An Experimental Study on Biocompatibility of Human Hair Keratin Artificial Tendon Material
- VernacularTitle:人发角蛋白人工腱材料体外生物容性的实验研究
- Author:
Sheng LU
;
Qixun LI
;
Yueqiu LIN
- Publication Type:Journal Article
- Keywords:
Biocompatibility;
Artificial tendon;
Tissue engineering
- From:
Journal of Chinese Physician
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the biocompatibility of human hair keratin artificial tendon(HHKAT) material in vitro. Methods Human embryonic tendon cell (HETC) was incubated with various concentrations (100%,50%,10%) of extracted liquid of HHKAT material for 1,3,5 and 7 days, respectively. Collagen I expression in HETC was detected by immunocytochemistry. The effects of HHKAT material on the proliferation and ultrastructure of HETC were observed. Results Various concentrations of extracted liquid of HHKAT had no effect on the morphologic, collagen I expression and ultrastructure of HETC. HETC could adhere, grow and proliferate on the surface of HHKAT material. Conclusion HHKAT is a medical biomaterial with good biocompatibility in vitro.
