Relationship between the Expression of Caveolin-1 and Pathological Grade, Clinical Stage in Bladder Carcinoma
- VernacularTitle:Caveolin-1的表达及其与膀胱癌病理分级及临床分期的关系
- Author:
Yi WANG
;
Hongmei LUO
;
Luoyan YANG
- Publication Type:Journal Article
- Keywords:
Caveolin-1;
Bladder Carcinoma;
Immunohistochemistry
- From:
Journal of Chinese Physician
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the expression of caveolin-1 and pathological grade, clinical stage in bladder carcinoma. Methods Caveolin-1 expression was detected in 63 cases of bladder carcinoma and 10 cases of normal bladder epithelial tissue using SABC immunohistochemistry. The clinical and pathological data of the patients were collected and used to make statistical analysis. Results The normal bladder mucosal epithelia had not caveolin-1 expression, while the positive rate of caveolin-1 expression was 34.92% in bladder carcinoma. The positive rates of caveolin-1 expression in the grades I, II and III of bladder carcinoma were 0%, 2.86%, 54.28%, respectively, which had a significant difference(P
