Study on the Stability of the Mixture of Cefradine for Injection and Ornidazole Sodium Chloride Injection
- VernacularTitle:注射用头孢拉定与奥硝唑氯化钠注射液的配伍稳定性考察
- Author:
Zhennan XIONG
;
Hua LI
- Publication Type:Journal Article
- Keywords:
HPLC;
Cefradine for injection;
Ornidazole sodium chloride injection;
Compatibility;
Stability
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the stability of the mixture of cefradine for injection and ornidazole sodium chloride injection.METHODS:HPLC method was adopted in which the Nova-pak C 18 was taken as the chromatographic column,methanol-water(35∶65)was taken as the mobile phase with detection wavelength at240nm.The contents were determined after mixing of cefradine for injection and ornidazole sodium chloride injection under the room temperature within8hours,and the appearance of the solution was observed and its pH value was determined.RESULTS:No significant differences were found in terms of the appearance,pH value and the contents of the mixed solution.CONCLUSION:The mixture of ornidazole for injection and cefradine sodium chloride injection can be used under room temperature within8hours of mixing.
