Optimization of Matrix Composition and Technique for Acne Emulsion by Orthogonal Design Method
- VernacularTitle:正交设计试验法优选痤疮乳剂的基质及工艺
- Author:
Maolin SHANG
;
Disheng WANG
- Publication Type:Journal Article
- Keywords:
Orthogonal design method;
Acne emulsion;
Matrix composition;
Technique
- From:
China Pharmacy
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize matrix composition and technique for acne emulsion.METHDOS:Oil phase,emulsifier and emulsify temperature were selected as variable factors using orthogonal design method,and table L 9 (3 4 )was used for the experiment.RESULTS:The optimum matrix composition and technique were stearic acid of15g,liquid paraffin of13g,vaseline of20g,trietha nolamine of3g,emulsifying temperature of85℃.CONCLUSIONS:The acne emulsion prepared by this kind of composition and technique accord with the stipulation of Chinese Pharmacopoeia.
