Relationship Between Interleukin-6 Gene Promoter Polymorphisms and Plasma Lipid, Platelet Count
- VernacularTitle:白细胞介素-6基因启动子多态性与血脂及血小板计数关系的研究
- Author:
Yesheng WEI
;
Yunguang LIU
;
Zhuang LI
- Publication Type:Journal Article
- Keywords:
Interleukin-6;
Gene Polymorphism;
Platelet;
Plasma lipid
- From:
Journal of Chinese Physician
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the distribution of IL-6 gene promoter 572C/G, 634C/G polymorphisms in Han population of Guangxi province, and analyze the relation between IL-6 gene polymorphisms and plasma lipid, platelet count. Methods Polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP) was used to detect IL-6 genotype in 198 healthy Han adults. At the same time the plasma lipid level and platelet count were determined by routine methods. Results Serum lipid levels had not significant difference among the different genotypes of IL-6 (P
