Expression of Matrix Metalloproteinase-9 and Interleukin-6 of Amniotic Fluid in Patients with Infection of Amniotic Cavity
- VernacularTitle:基质金属蛋白酶-9和IL-6在羊膜腔感染中的表达
- Author:
Xiaomei ZHOU
;
Wenhui YU
;
Xialing WANG
- Publication Type:Journal Article
- Keywords:
Amniotic fluid;
Matrix metalloproteinase-9;
Interleukin-6;
Infection, amniotic cavity
- From:
Journal of Chinese Physician
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the role of matrix metalloproteinase-9(MMP-9) and interleukin-6 (IL-6) of amniotic fluid (AF) in predicting infection of amniotic cavity. Methods Eighty-four cases of sigle foetus women with premature delivery, premature rupture of foetal membranes,or suspicious infection of amnitotic cavity were enrolled in this study. AF was obtained by transabdominal amniocentesis before starting any treatment.Infection of amniotic cavity was defined when AF bacterial culture was positive. The contents of glucose, leukocytes, MMP-9,and IF-6 in AF were determined. Results The levels of MMP-9 and IL-6 in AF were significantly higher in women with infection of amniotic cavity than those in women without. In women with infection of amniotic cavity, MMP-9 level was significantly correlated with IL-6 level (r=0.813,P
