Study of the Preparation Technology and Stability of Lornoxicam for Injection
- VernacularTitle:注射用氯诺昔康的制备及稳定性研究
- Author:
Guiying FU
;
Hua GUO
;
Xiuping ZUO
;
Hui GAO
;
Mingling WEN
- Publication Type:Journal Article
- Keywords:
Lornoxicam;
Injection;
Preparation;
Stability
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare Lornoxicam for injection and to study its stability.METHODS:The formular and pre paration technology of Lornoxicam for injection was optimized with the index of contents,the related substances and pH value;3batches of samples'stability was investigated.RESULTS:The best formula was found to be the following:4.0g of lornoxicam,4.0g of propylene glycol,100g of mannitol and sufficient quantum of1mol/L caustic soda,3batches of sample preparations man ufactured under this formula were found to be stable in quality in the accelerated,room temperature storage test under the condition of commercial packing.CONCLUSION:The formula design was reasonable and the preparation technology was feasible.
