Effects of Folic Acid Combined Methylcobalamin in the Treatment of the Patients that Are Uremia Ac-companied by Hyperhomocysteinemia
- VernacularTitle:叶酸联合甲钴胺对尿毒症伴高同型半胱氨酸血症患者的影响
- Author:
Shuming CHEN
;
Shaobo DING
;
Dongwen ZHENG
;
Liqing ZHOU
;
Hongying HUANG
;
Weiguo YE
;
Yulong HUANG
;
Ling GUAN
- Publication Type:Journal Article
- Keywords:
Folic acid;
Methylcobalamin;
Uremia;
Hyperhomocysteinemia
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the plasma total homocysteine(tHcy)level in the uremia patients and to study the therapeutic effects of folic acid combined with methylcobalamin in the intervention treatment of uremia patients with homo-cysteinemia.METHODS:Levels of plasma tHcy of60uremia patients(treatment group)and40normal subjects(control group)were determined both before treatment and8weeks after intervention treatment with folic acid combined with methylcobal-amin.RESULTS:The plasma level of tHcy in uremia patients were significantly higher than that in the normal subjects(P