Effect of tetracycline combined with anti-inflammation drug a nd tetracycline on the level of serum IgG antibody titer in early-onset periodonti tis
- VernacularTitle:结合四环素和抗炎剂的牙周治疗对早发性牙周炎抗牙龈卟啉菌抗体水平的影响
- Author:
Xiuqin ZHANG
;
Shiguang HUANG
;
Ying ZHANG
;
Fangli L
- Publication Type:Journal Article
- Keywords:
Periodontitis;
Porphyromonas, gingivalis;
Ant ibodies;
Tetracyclines
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: The purpose of this study was to eva lu ate the effect of tetracycline combined with anti-inflammation drug on the serum antibody level against porphyromonas gingivalis (Pg) in patients with early-ons et periodontitis (EOP). METHODS: The study population consisted of 12 individuals with e arly-onset periodontitis, 16 patients with adult periodontitis (AP) and 12 perio dontally healthy subjects (HS). Clinical examination and recordings of probing p ocket depth (PPD), periodontal attachment level (PAL) and bleeding on probing (B OP) were performed prior to treatment and at three months following the periodontal treatment. The serum antibody titer against Pg in patients with EOP was measured at diagnosis and at the termination of treatmeat. RESULTS: A significant improvement was observed in probing pocke t depth, periodontal attachment level and gingival bleeding index post treatment for three months. The serum IgG antibody titer against porphyromonas ging ivalis was decreased significantly after the treatment. CONCLUSION: Our results demonstrate that mechanical periodontal treatment combined with tetracycline and anti-inflammation drug provides clinica lly favorable results in patients with early-onset periodontitis.