Effects of aging on sperm maturation and fertility in mice
- VernacularTitle:衰老对小鼠精子成熟和受精能力的影响
- Author:
Qiuju CHEN
;
Weijie ZHU
;
Jing LI
- Publication Type:Journal Article
- Keywords:
Aging;
Mice;
Spermatozoa;
Fertilization, in vitro
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effects of aging on sperm maturation and fertility in mice. METHODS: Sperm of caput epididymides and cauda epididymides were obtained from Kunming mice aged 6 months (n=15, as control) and 18 months ( n=15). Sperm parameters including sperm density, viability, motility and nor mal morphological rate were recorded. Sperm of cauda epididymides was observed b y transmission electron microscope. The fertility potential and embryo developme ntal competence were performed by in vitro fertilization and embryo culture. RESULTS: Sperm motility, density and normal morphological rate i n aged mice were lower than those in control (P