Effects of Bone-tonifying Capsule on Bone Morphology and Serum TNF-?of the Osteoporosis Model Rats
- VernacularTitle:益骨胶囊对骨质疏松模型大鼠骨形态学及血清TNF-?水平的影响
- Author:
Li HOU
;
Ronghua ZHANG
;
Li YANG
;
Xiaofeng ZHU
- Publication Type:Journal Article
- Keywords:
Bone-tonifying capsule;
Osteoporosis;
Rats;
Bone morphology;
TNF-?
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the effects of bone-tonifying capsule on bone morphology and serum TNF-?level of the osteoporosis(OP)model rats.METHODS:The rats were divided into sham operation group,model group and treatment group.OP model were established by removing ovaries of both sides in both the model group and the treatment group by o-variectomy,then the bone density of each group was determined;the bone morphology was observed in the decalcified section of bone tissue;the concentration of serum estradiol(E 2 )and TNF-?level were determined by radioimimunoassay.RESULTS:Compared with the sham group,the bone density and serum E 2 level lowed yet the TNF-?level increased in the model group(P
