Comparative Study on the Vitro Antibacterial Activity of Domestic and Imported Teicoplanin against 224 Strains of Enterococci
- VernacularTitle:国产与进口替考拉宁对224株肠球菌的体外抑菌活性比较研究
- Author:
Zhongxing LI
;
Xiuhua WANG
;
Jingfang YANG
;
Dongyan SHI
;
Jihong LI
;
Jingbo CHEN
- Publication Type:Journal Article
- Keywords:
Teicoplanin;
Enterococci;
Antibacterial activity
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the vitro antibacterial activity of domestic teicoplanin against224strains of enterococ-ci.METHODS:Determination of MIC of domestic teicoplanin against169strains of entercococcus faecalis and51strains of E.faecium was tested by agar dilution method,and its antibiotic effect was compared with that of the imported teicoplanin and other antibiotics.RESULTS:The MIC 50 of domestic teicoplanin against169strains of E.faecalis and51strains of E.faecium were0.125,0.25?g/ml respectively,MIC 90 were2,1?g/ml respectively;The MIC 50 of imported teicoplanin against E.faecalis and E.faecium were0.25,0.25?g/ml respectively,MIC 90 were1,0.5?g/ml respectively.CONCLUSION:Two kinds of te-icoplanin have strong antibacterial activity against224strains of enterococci;the sensitivity of224strains of enterococci to both kinds was100%.
