Mechanism of Ligustrazine in Treating Cerebral Infarction
- VernacularTitle:川芎嗪治疗脑梗死的临床机制研究
- Author:
Xiaomin LI
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Ligustrazine;
Tumor necrosis factor;
Endothelin;
Nitric oxide
- From:
China Pharmacy
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the mechanism of ligustrazin in treating cerebral infarction.METHODS:60healthy volunteers were assigned to group A,and68patients with cerebral infarction were allocated o group B,the levels of TNF-?,ET-1and NO in plasma were determined,the pre-treatment and post-treatment results of these indices were compared in group B and they were all compared with those in group A.RESULTS:The levels of plasma TNF-?and ET-1were sig-nificantly higher and NO were remarkably decreased in patients group B as compared with group A(P
