Effect on cell apoptosis and Bax/Bcl-2 gene expression of implanted human breast cancer cells in nude mice by applying RNAi to silence STAT3 gene
- VernacularTitle:应用RNAi沉默STAT3基因促裸鼠移植瘤细胞凋亡及对Bax/Bcl-2基因表达的影响
- Author:
Yu WANG
;
Yingchao ZHANG
;
Yuzhuo PAN
;
Xuejian ZHAO
;
Wenzeng GUAN
- Publication Type:Journal Article
- Keywords:
BREAST NEOPLASIS/genet;
APOPTOSIS;
GENE EXPRESSION;
GENE,Bax;
GENE,Bcl-2;
RNAi TECHNIQUE;
ACTIVATERS OF TRANSCRIPION 3;
SILENCE SIGNAL TRANSDUCERS
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). Conclusions Silencing STAT3 gene can decrease STAT3 gene expressions , increase Bax gene expressions , induce cell apoptosis and suppress the tumor growth in the human breast carcinoma model by the RNAi technology .
