c-fos Expression in Medial Vestibular Nucleus of Guinea Pigs After Unilateral Labyrinthectomy
- VernacularTitle:豚鼠一侧迷路毁损后前庭内侧核c-fos表达
- Author:
Meizhen GU
;
Shankai YIN
- Publication Type:Journal Article
- Keywords:
Medial vestibular nuclei(MVN);
C-fos;
Ge ne expression;
Unilateral labyrinthectomy(UL)
- From:
Journal of Audiology and Speech Pathology
1998;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the c-fos ex pr ession in guinea pigs' medial vestibular neuleus (MVN) following unilateral laby rinthectomy (UL). Methods Twenty-seven SCO guinea pigs were randomly divide d into nine groups, three in each group. After resection of right labyrinth,th e immunohistological staining of c-fos was performed. Fos-like immunoreactivity (FLI) was analyzed at fifteen minutes, and 1?2?6?8?12 and 24 h, and 2 and 7 days after UL. Results Results showed no Fos expression in the control g roup. By contrast, Fos was consistently induced in the UL guinea pigs. Asymmetri cal labeling was found in the bilateral medial vestibular nucleus, with more Fos -like neurons in the ipsilateral MVN of the lesioned side than that in the contr alateral MVN(P
