A preliminary study on chemical bile duct embolization for chemical hepatectomy
- VernacularTitle:应用胆道化学性栓塞进行化学性肝切除的实验研究
- Author:
Fuyu LI
;
Sheng HE
;
Ning LI
;
Jingqiu CHENG
;
Jiahong DONG
;
Mingming ZHANG
;
Lisheng JIANG
;
Nansheng CHENG
- Publication Type:Journal Article
- Keywords:
Bile duct;
Embolization;
Hepatectomy;
Hepatolithiasis
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility, effect and mechanism of chemical bile duct embolization for chemical hepatectomy. Methods Phenol or absolute ethanol plus cyanonacrylate were employed as embolization agents. Histology, Fas and TGF-? 1 measurement were used to evaluate the result. Results Phenol plus cyanonacrylate effectively destroyed and embolized intrahepatic biliary duct, leading to complete disappearance of hepatocytes in the periphery of embolization lobe and thereby achieving the effect of chemical hepatectomy. Expression of Fas and TGF-? 1 in phenol embolism group (88.90?38.10, 185.22?70.39) and ethanol embolism group (72.39?29.51, 163.56?51.75) were higher than those in biliary duct ligated group (26.31?12.07, 74.84?40.73) ( P