The Effects of Zhu Ling Decoction and Alisma Orientalis on Osteopotin mRNA Expression in the Experimental Rat Model of Renal Stone
- VernacularTitle:肾结石大鼠Osteopotin mRNA的表达及猪苓汤和泽泻对其表达的影响
- Author:
Zhen LAI
;
Xiaoying GENG
;
Yaobang WNAG
- Publication Type:Journal Article
- Keywords:
Zhu Ling decoction;
Alisma orientalis;
Osteopontin mRNA;
Reverse transcription polymerase chain reaction
- From:
Journal of Chinese Physician
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of Zhu Ling decoction and Alisma orientalis on the osteopotin mRNA expression in the experimental rat model of renal stone. Methods The experimental rat model of renal stone was set up using glyoxylic acid. Osteopontin mRNA expression in the renal tissues in the experimental rat model of renal stone was detected by RT-PCR. Results Glyoxylic acid obviously increased osteopontin mRNA expression in the renal tissues. Zhu Ling decoction and Alisma orientalis remarkably decreased the expression of osteopontin mRNA in the renal tissues. Conclusion Zhu Ling decoction and Alisma orientalis could decrease the osteopotin mRNA expression in the renal tissues in the experimental rat model of renal stone. The results were helpful for prevention and treatment of renal stone.
