Relationship Between the Invasion of Pituitary Adenomas and Expressions of MMP-9,Ki-67 and nm23
- VernacularTitle:垂体腺瘤侵袭性与MMP-9、Ki-67、nm23表达的相关性研究
- Author:
Aihua LIU
;
Wei HUANG
;
Shaowen XIAO
- Publication Type:Journal Article
- Keywords:
Pituitary adenoma;
Invasion;
Immunohistochemistry
- From:
Journal of Chinese Physician
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the invasion of pituitary adenomas and expressions of MMP-9,Ki-67 and nm23. Methods The expressions of MMP-9,Ki-67 and nm23 were examined by immunohistochemical Elivision methods in 78 cases of pituitary adenomas. Of them,40 cases were invasive pituitary adenomas and, 38 cases were noninvasive pituitary adenomas. Results The expression levels of MMP-9 and Ki-67 in the invasive pituitary adenomas were significantly higher than those in the noninvasive ones (P
