Content Determination of Dexamethasone Sodium Phosphate in Compound Baifu Pellicles by RP-HPLC
- VernacularTitle:反相高效液相色谱法测定复方白氟膜剂中地塞米松磷酸钠的含量
- Author:
Xuemei HUANG
;
Ying CHEN
- Publication Type:Journal Article
- Keywords:
RP-HPLC;
Compound Baifu Pellicles;
Dexamethasone Sodium Phosphate;
Content determination
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a RP-HPLC method for content determination of Dexamethasone Sodium Phos-phate in Compound Baifu Pellicles.METHODS:A X-Terra RP 18 column was used,the mobile phase was Methanol-0.34%KH 2 PO 4 solution-triethylamine(52∶48∶0.2),detecting wavelength was242nm and the flow rate was0.7ml/min.RE-SULTS:Dexamethasone Sodium Phosphate was in the good linear range when the sample size was between0.0403?g～2.016?g(r=0.9999,n=3).The average recovery rate was99.85%(RSD=3.00%,n=6).CONCLUSIONS:The established method is convenient,accurate,replicable,which can be applied to quality control of Compound Baifu Pellicles.
