Expression of nuclear factor kappa B in the spinal ganglions of adjuvant arthritis rats
- VernacularTitle:佐剂关节炎大鼠脊神经节中核因子kappa B表达的研究
- Author:
Hui SHEN
;
Jing LU
;
Weiguo XIAO
;
Xiubi FANG
- Publication Type:Journal Article
- Keywords:
Arthritis, rheumatoid;
Arthritis, experimental;
Spinal nerves;
NF-kappa B
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the expression of nuclear factor kappa B (NF-?B) in the L 1-L 4 spinal ganglions of adjuvant arthritis (AA) rats, to explore the neuroendocrinoimmunological mechanism of rheumatoid arthritis (RA). METHODS: The expression of the NF-?B protein was detected by immunohistochemistry method and the alteration of the active NF-?B protein (nuclear protein) was investigated by Western blotting analysis. RESULTS: The expression of NF-?B protein in L 1-L 4 spinal ganglions of AA rats was much higher than that in the healthy controls ( P
