Experiment of the Photostability of the Levofloxacin Hydrochloride Injection
- VernacularTitle:不同光照对盐酸左氧氟沙星注射液稳定性的影响
- Author:
Jinyue CHEN
;
Juan WEN
;
Minyang GONG
;
Liying LIANG
- Publication Type:Journal Article
- Keywords:
Levofloxacin hydrochloride injection;
Light illumination;
Stability;
TLC
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the photostability of the levofloxacin hydrochloride injection. METHODS: The content of levofloxacin hydrochloride was determined and its UV spectra changes were observed after being lighted by three different light sources-the UV light, the sunlight and the natural light for different periods of time. Whether there is any decomposed product or not was determined by TLC. RESULTS: There were decompositions of levofloxacin hydrochloride injection subjected to illumination from three light resources, with that under the sunlight decomposed faster; Rf value under TLC of the decomposed product was found to be 0.72. CONCLUSION: Levofloxacin hydrochloride injection should be kept away from UV light, the sunlight and the natural light.
