The expression and significance of CK20 mRNA in patient of gastric cancer
- VernacularTitle:实时定量荧光逆转录聚合酶链反应检测胃癌患者血CK20 mRNA及其意义
- Author:
Wenjun CHEN
;
Xiaoming YUAN
;
Linbo WANG
;
Shu ZHENG
;
Jinmin WU
;
Xing ZHANG
;
Jiang CAO
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Micrometastasis
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical significance of CK20 mRNA expression in the blood of gastric cancer patients. Methods Expression of CK20 mRNA was detected by FQ-PCR in preoperative peripheral blood, tumour drainage blood and postoperative peripheral blood in 55 gastric patients and 60 blood donors.Results There was no positive expression of CK20 mRNA of peripheral blood in 60 healthy blood donors.The expression rate of CK20 mRNA was 45.45% in preoperative peripheral blood.The expression rate was higher in stage Ⅲ Ⅳ than stage ⅠⅡ patients ( P