The Effects of ?-tocopherol on Bcl-2 Protein Expression of Spermatogenic Cells in Rats with Varicocele
- VernacularTitle:?-生育酚对精索静脉曲张大鼠生殖细胞Bcl-2蛋白表达的影响及意义
- Author:
Qiang XIA
;
Xiaobin ZHANG
;
Jie ZHANG
- Publication Type:Journal Article
- Keywords:
Animal model;
?-tocopherol;
Varicocele;
Bcl-2 protein;
Cell apoptosis
- From:
Journal of Chinese Physician
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effects of ?-tocopherol on Bcl-2 protein expression of spermatogenic cells in experimental varicocele rats. Methods Thirty adult male Wistar rats were randomly divided into 3 groups(n=10): treatment group (TG) was intramuscularly injected ?- tocopherol (0.5mg/100g body weight, one time daily for 4 weeks) after establishing varicocele model by partial ligation of the left renal vein for 4 weeks, operation control group (OCG)and sham operation group (SOG). After 8 weeks Bcl-2 protein expression in the testes tissues was detected by immunohistochemical method. Results The weight of left testes in TG was obviously heavier than that in OCG(P
