Elevated levels of serum IL-6, ICAM-1 and P-selectin in stable survivors with liver transplantation
- VernacularTitle:肝移植患者血清白细胞介素-6、细胞间粘附分子-1和P-选择素高水平表达分析
- Author:
Yunle WAN
;
Shusen ZHENG
;
Lihua WU
;
Wenjin ZHANG
;
Lin ZHOU
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Interleukin-6;
Interc ellular adhesion molecule-1;
P-selectin
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05). However, a significant higher percentage of CD3+CD25+ T cells was found in stable liver transplantation group as compared to healthy group ( P0.05). There was not found no regular change of serum cytokine s (IL-6, TN F-?) and adhesion molecules (ICAM-1, P-selectin) in 6 liver transplanted patien ts during post-operation from day 1 to day 30, indicating that was associated wi th the different status of patients before or after transplantation. CONCLUSIONS: Our data suggesting that increased levels of ICAM-1 and P-selectin, appears to participate in the processing of immunoregulation to transplanted livers, whereas elevated concentrations of IL-6 appear to be involv ed in the repair of the injury induced by TNF-? in allo-transplanted livers.
