Study on in Vitro Percutaneous Absorption of Galanthamine Cream
- VernacularTitle:加兰他敏乳膏体外透皮吸收实验研究
- Author:
Weijuan ZHAO
;
Jiaming BIAN
;
Mei ZHANG
;
Xuqun ZHANG
- Publication Type:Journal Article
- Keywords:
Galanthamine;
Azone;
Percutaneous absorption
- From:
China Pharmacy
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the in vitro percutaneous permeability of galanthamine cream.METHODS:Using iso?lated mouse's skin as barrier to permeation,the promoting effect of azone in different concentrations on permeation of galanth_ amine was studied.RESULTS:Azone could obviously enhence the permeability of galanthamine through skin.The steady flux of galanthamine cream containing2%and5%azone increased56.12%and23.29%respectively.CONCLUSION:Galanthamine cream has good percutaneous permeability and2%azone promotes the permeability best.
