Preparation,Quality Control and Therapeutic Effect Observation of Chlorphenamine Cream
- VernacularTitle:扑尔敏霜剂的研制与质量控制及临床疗效观察
- Author:
Fang LI
;
Wen QIU
;
Sanmao WU
- Publication Type:Journal Article
- Keywords:
Chlorphenamine;
Cream;
Quality control;
Clinical application
- From:
China Pharmacy
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare chlorphenamine cream,establish its quality control and observe its clinical therapeutic effect.METHODS:Chlorphenamine cream was prepared by emulsification,the content was determined by UV spectrophotom?etry and the stability of which was observed by the initial average rate method.RESULTS:The linear range of chlorphenamine was10～30?g/ml(r=0.9999);the average recovery rate was101.25%,RSD=1.28%;the total effective rate in the clinical application was97.66%.CONCLUSION:The cream is stable in quality and its therapeutic effect is reliable and safe.
