Study on the Preparation and Quality Control of Papaverine-nitroglycerin Ointment
- VernacularTitle:罂硝软膏的制备及质量控制
- Author:
Wei ZHANG
;
Dianquan LIU
;
Jinhong XUE
;
Pengchuan LIU
- Publication Type:Journal Article
- Keywords:
Papaverine-nitroglycerin ointment;
Preparation;
Quality control
- From:
China Pharmacy
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare papaverine-nitroglycerin ointment and to establish a method for its quality control.METHODS:Nitroglycerin,papaverine hydrochloride and diclofenac potassium were used as basic remedies to prepare oint?ment.The contents of nitroglycerin,papaverine hydrochloride and diclofenac potassium were determined by UV-spec?trophotometric methods.RESULTS:The average recovery rates of Nitroglycerin,papaverine hydrochloride and diclofenac potassium were100.65%、99.86%、100.55%respectively,and RSD equal to0.4945%、0.1719%、0.3205%respectively(n=3). CONCLUSION:The ointment preparation is feasible in technique,reliable in quality control and stable in quality.