Invasive Breast Carcinoma Arising in Microglandular Adenosis: Two Case Reports.
10.4048/jbc.2013.16.4.432
- Author:
Jung Eun CHOI
1
;
Young Kyung BAE
Author Information
1. Department of Surgery, Yeungnam University College of Medicine, Daegu, Korea.
- Publication Type:Case Report
- Keywords:
Breast;
Carcinoma;
Fibrocystic breast disease
- MeSH:
Adult;
Biopsy;
Biopsy, Large-Core Needle;
Breast*;
Carcinoma, Intraductal, Noninfiltrating;
Female;
Fibrocystic Breast Disease*;
Follow-Up Studies;
Humans;
Mastectomy, Modified Radical;
Middle Aged;
Muramidase;
Sentinel Lymph Node Biopsy
- From:Journal of Breast Cancer
2013;16(4):432-437
- CountryRepublic of Korea
- Language:English
-
Abstract:
Microglandular adenosis (MGA) is a rare benign disease that shows an infiltrative growth pattern of small glands, and it may progress to include atypia and carcinoma. Here we report two cases of breast carcinoma arising in MGA. Case 1 was a 44-year-old woman with a previous history of ductal carcinoma in situ in her right breast. During a follow-up, a 1.8 cm mass-like lesion was found in her left breast. An excisional biopsy suggested that the lesion was breast carcinoma. Case 2 was a 57-year-old woman with a 2.9 cm mass in her right breast. A core needle biopsy of the lesion suggested invasive carcinoma. Both patients underwent modified radical mastectomy with sentinel lymph node biopsy. Both tumors lacked a myoepithelial cell layer and stained positively for S-100, lysozyme, and alpha1-antitrypsin, which is typical of MGA. Both cases showed invasive carcinoma arising in MGA.
