Relationship between the p33~(ING1b) Protein Expression and Differentiated Degree in Human Gastric Carcinoma
- VernacularTitle:P33~(ING1b)蛋白表达与胃癌分化程度的关系
- Author:
Xiutao HE
;
Jianhua LU
;
Jiaxin TANG
- Publication Type:Journal Article
- Keywords:
p33 ING1b;
Differentiation;
Gastric carcinoma;
Immunohistochemistry
- From:
Journal of Chinese Physician
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the p33 ING1b protein expression and differentiated degree in human gastric carcinoma. Methods p33 ING1b protein expression was detected by S-P immunohistochemical method in gastric carcinoma and normal gastric mucous tissues. Results The positive rates of p33 ING1b protein expression were 75% (15/20) in well-differentiated, 55% (11/20) in moderate-differentiated and 15% (3/20) in poor-differentiated gastric carcinoma, respectively. The positive rate of p33 ING1b protein expression in gastric carcinoma was significantly lower than that in normal gastric mucosa (100%, 60/60) (P
