Effects of Yiweikang Capsule on Recovery of Gastric Mucosa of Model Rats with Gastritis and Gastric Ulcer
- VernacularTitle:益胃康胶囊对胃炎、胃溃疡模型鼠的胃粘膜修复作用研究
- Author:
Lingjing HU
;
Min YANG
;
Xiaomei HU
;
Huimin XIE
- Publication Type:Journal Article
- Keywords:
Yiweikang capsule;
Gastritis;
Gastric ulcer;
Recovery of gastric mucosa
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the protective effects of Yiweikang(YWK)capsule on gastric mucosa of the model rats with gastritis and gastric ulcer.METHODS:The experimental rats were randomly divided into five groups:YWK high-dosage group,YWK moderate-dosage group,YWK low-dosage group,positive control group(treated with drenched cime?tidine capsule,0.1g/kg),and negative control group(provided with drenched isovolumic distilled water or sodium chloride)in order to observe the effects of YWK for excitable gastric ulcer in mice and gastric ulcer in rats induced by alcohol and pylorus-ligature.RESULTS:Compared with the negative controls,gastric acid,gastric juice and ulcer indices in YWK group declined,most significantly in high-dosage group.CONCLUSION:YWK in oral administration has preventive effects for excitable ulc_ er,alcohol induced ulcer and pylorus-ligature induced ulcer.It also can help the recovery of gastric mucosa of ulcer model rats.
