Determination of Mizolastine Tablet by RP-HPLC
- VernacularTitle:反相高效液相色谱法测定咪唑斯汀片含量
- Author:
Kun TANG
- Publication Type:Journal Article
- Keywords:
RP-HPLC;
Mizolastine tablet;
Content determination
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBIECTIVE:To establish a method for the determination of mizolastine in tablet.METHODS:HPLC was carried out,using a HiQ sil C 18 column and a mobile phase consisting of0.025mol/L KH 2 PO 4 buffer solution-acetonitrile(72∶28).The flow rate was0.5ml/min.RESULTS:The standard curve was linear over the range of4.16～416?g/ml of mizolastine(r=0.9998).The recovery of mizolastine was99.98%(RSD=0.44%,n=3).CONCLUSION:The proposed method is sim?ple,accurate and can be used for the content determination of Mizolastine tablet.
