Influence of Mixed Decoction of Cortex Phellodendri,Radix Glycyrrhizae and Ramulus Loranthi on Ex-traction Rate of Berberine
- VernacularTitle:黄柏与甘草及桑寄生共煎对小檗碱提取率影响的研究
- Author:
Qiaoru LI
;
Peng ZHANG
;
Shihu CHEN
;
Jiangping LIAN
;
Xiaochuan LI
- Publication Type:Journal Article
- Keywords:
Cortex Phellodendri;
Radix glycyrrhizae;
Ramulus loranthi;
Mixed decoction;
Berberine;
Extraction rate
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the infuence of mixed decoction of Cortex Phellodendri,Radix Glycyrrhizae and Ramu?lus Loranthi on extraction rate of berberine.METHODS:The extraction amount from Cortex Phellodendri,Radix Glycyrrhizae and Ramulus Loranthi mixed decoction was determined by HPLC.The HPLC conditions were:Hypersil BDS C 18 column;mobile phase,acetonitrile-33mmol/L KH 2 PO 4 -triethylamine(20∶72∶0.1);detecting wavelength,345nm;column temperature25℃;flow fate1.0ml/min.RESULTS:Decoction of Cortex Phellodendri,Radix Glycyrrhizae and Ramulus Loranthi in combi?nation obviously decreased the extraction rate of berberine.CONCLUSION:Cortex Phellodendri should be extracted separately in formulating extract technic for preparations containing above-mentioned herbs.