Effect of naoreqing oral liquid on cAMP contents of hypothalamus and cerebrospinal fluid in endogenous pyrogen-induced febrile rabbits
- VernacularTitle:脑热清对EP性发热家兔下丘脑及脑脊液cAMP含量的影响
- Author:
Xiaoli YUE
;
Yufeng JIANG
;
Zhiqin LIU
;
Yongping FAN
;
Wenrong WANG
;
Liwei REN
;
Qifu HUANG
;
Yiming HU
- Publication Type:Journal Article
- Keywords:
Endogenous pyrogen;
Fever;
Cyclic AMP;
Naoreqing
- From:
Chinese Journal of Pathophysiology
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the antipyretic mechanism of Naoreqing (NRQ) oral liquid, a Chinese medicine. METHODS: ① Fever models of rabbits were established by intravenous. injection of endogenous pyrogen (EP). ② The antipyretic action of NRQ were observed. ③ cAMP contents in the hypothalamus (HP) and the cerebrospinal fluid (CSF) were determined by radioimmunoassay. RESULTS: ① NRQ obviously reduced body temperature of febrile rabbits induced by EP (P
