Preparation and Quality Control of Minoxidil Gel
- VernacularTitle:米诺地尔凝胶的制备及质量控制
- Author:
Yan ZHOU
;
Jie ZHANG
- Publication Type:Journal Article
- Keywords:
Minoxidil;
Gel;
Preparation;
Quality control
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare the minoxidil gel and to establish a quality control method for the gel.METHODS:Carbopol934was used as the gel base;the content of minoxidil was determined with UV-spectrogram and the stability test was performed.RESULTS:There was a good linearity of calibration curve of minoxidil in range of2～10?g/ml(r=0.9999).The average recovery was99.8%,and RSD was0.67%(n=4).The gel was stable.CONCLUSION:The gel is reasonable in for?mulation,simple and accurate in quality control,as well as satisfactory in stability.
