The Level Change of Serum Superoxide Dismutase in Patients with Severe Acute Respiratory Syndrome
- VernacularTitle:严重急性呼吸综合征患者血清超氧化物歧化酶含量的动态观察
- Author:
Yixiu YE
;
Wei WANG
;
Hongmin LI
- Publication Type:Journal Article
- Keywords:
Severe acute respiratory syndrome (SARS);
Infectious atypical pneumonia;
Serum;
Superoxide dismutase
- From:
Journal of Chinese Physician
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the level change of serum SOD in patients with severe acute respiratory syndrome (SARS). Methods The levels of serum SOD in 66 patients with SARS were measured by RIA, and compared with controls. Results The levels of serum SOD in patients with SARS were significantly lower than those in controls, and in severe type of SARS patients were lower than those in the other types. The levels of serum SOD in the recovery stage of SARS patients increased, but still was lower than those in controls. Conclusion Excessive free radicals were produced in patients with SARS, and SOD was depleted. The level change of SOD in patients with SARS may reflect state of disease. Dynamic detection of serum SOD level is helpful for monitoring state of SARS. It may be an important therapeutic measure that excessive free radicals were eliminated from SARS patient body.
