A Clinical Study on Treatment of Late-stage Malignant Tumors by Transplantation of Fetal Thymus
- VernacularTitle:胎儿胸腺移植治疗晚期恶性肿瘤的临床研究
- Author:
Aihua YAN
;
Hongyi YUE
;
Lichun CUI
- Publication Type:Journal Article
- Keywords:
Thymus transplantation;
Malignant tumor;
Microvascular surgery;
Fetus
- From:
Journal of Chinese Physician
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of fetal thymus transplantation on enhancing the immunity of patients with late-stage malignant tumors. Methods The whole thymus of 24~32 weeks fetus was transplanted into the forearm of the patients with late-stage milignant tumors by microvascular surgery. The levels of serum IgA,IgG and IgM were measured before and at the third, 6th and 12th months after operation. No immunosuppressive regimen was performed in all the patients after operation. The follow-up period was 1 to 2 years. Results The clinical symptoms of all the patients improved after treatment, and no rejection reaction occurred. The levels of serum IgA,IgG and IgM significantly increased 3,6 and 12 months after treatment(t≥4.23,P