Study on Extraction Technique of Compound Liuyuexue Granules
- VernacularTitle:复方六月雪颗粒提取工艺研究
- Author:
Jiang LI
;
Zhongshi HUANG
;
Weizhe JIANG
;
Jun LIN
;
Renbin HUANG
- Publication Type:Journal Article
- Keywords:
Compound Liuyuexue granule;
Orthogonal design;
Oleanolic acid;
Total flavones
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the conditions of the extraction technique for compound Liuyuexue gran?ules.METHODS:The herbs in formulation were first extracted by ethanol percolating,then the dregs were decocted with water to be extracted once more.Taking oleanolic acid and total flavones as evaluation markers,the extraction technique in two-step process was evaluated by orthogonal design.RESULTS:The optimum condition of ethanol percolating process was that the crude herb powder was soaked by8-fold80%ethanol for24hours and the optimum condition of water decocting process was that the dregs were decocted for3times with12-fold water,1.5hour each time.CONCLUSION:The repeated experimental results are stable,and the contents of components for markers are high.The optimum conditions can be used for enlarged pro?duction.
