The Effects of Selenium and/or Vitamin E on NO and NOS in Heart,Liver,Kidney and Serum of Experimental Hyperlipidemic Rats
- VernacularTitle:硒和/或维生素E对实验性高脂血症大鼠心、肝、肾及血清中一氧化氮及一氧化氮合酶的影响
- Author:
Chunyang ZHOU
;
Xiang ZHANG
;
Chunyan CAI
;
Xian YU
;
Jun LEI
- Publication Type:Journal Article
- Keywords:
Selenium;
Vitamin E;
Hyperlipidemia;
Nitric oxide(NO);
Nitric oxide synthases(NOS)
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effects of selenium(Se)and/or vitamin E(VE)on the NO and NOS in heart,liver,kidney and serum of experimental hyperlipidemic rats.METHODS:SD rats were divided into5groups,administreated by Se and/or VE.After4weeks,the NO contents and NOS activities in heart,liver,kidney and serum were assayed by NO kit and NOS kit respectively.RESULTS:NO contents and NOS activities could be reduced in heart,liver,but increased in serum and kidney by high-fat feed(HFF).Meanwhile,VE and/or Se could increase the NO contents in all the experimental samples and NOS activities in heart,liver and kidney(P
