Detection of Bacterial Endotoxins in the Levofloxacin Hydrochloride Injection by Limulus Test
- VernacularTitle:盐酸左氧氟沙星注射液中细菌内毒素检查法的研究
- Author:
Yan PENG
;
Zhen SHI
;
Yi LUO
- Publication Type:Journal Article
- Keywords:
Levofloxacin hydrochloric injection;
Bacterial endotoxin;
Limulus test agent;
Interference test
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish the method for assaying bacterial endotoxins in levofloxacin hydrochloride injec?tion.METHODS:The interference test of3batches of levofloxacin hydrochloride injection with2kinds of limulus test agent was studied.RESULTS:The interference between the samples and limulus test agents was eliminable(below1.0mg/ml).The detection results were up to standard.CONCLUSION:The bacterial endotoxin in the sample can be examined by limulus test instead of pyrogen test in rabbits.
