Determination of the Content of Ephedrine Hydrochloride in Compound Baifu Pellicle by RP-HPLC
- VernacularTitle:反相高效液相色谱法测定复方白氟膜剂中盐酸麻黄碱的含量
- Author:
Ying CHEN
;
Xuemei HUANG
- Publication Type:Journal Article
- Keywords:
RP-HPLC;
Compound Baifu pellicles;
Ephedrine hydrochloride;
Content
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a HPLC method for determination of the content of ephedrine hydrochloride in compound Baifu pellicle.METHODS:A XTerra RP 18 column was used.The mobile phase was methanol-1%ammonium acetate solution(40∶60).The detection wavelength was215nm.The column temperature was30℃.The flow rate was0.6ml/min.RESULTS:There was good linearity of ephedrine hydrochloride in the range of0.1034?g~4.136?g(r=0.9994,n=3). The average recovery was101.29%(RSD=2.34%,n=6).CONCLUSION:This method is simple,accurate and repeatable,and can be used for quality control of compound Baifu pellicle.